Hui Chen Selected Research

Fluorouracil (Carac)

7/2022	Co-Delivery of 5-Fluorouracil and Paclitaxel in Mitochondria-Targeted KLA-Modified Liposomes to Improve Triple-Negative Breast Cancer Treatment.
1/2022	A randomized phase II trial of hepatic arterial infusion of oxaliplatin plus raltitrexed versus oxaliplatin plus 5-fluorouracil for unresectable colorectal cancer liver metastases.
1/2019	Effect of Grifola frondosa polysaccharide on anti-tumor activity in combination with 5-Fu in Heps-bearing mice.
1/2018	Phase II Study of Adjuvant Chemoradiotherapy Using Docetaxel/Cisplatin/5-Fluorouracil Before and After Intensity-modulated Radiotherapy With Concurrent Docetaxel in Patients With Completely (R0) Resected Gastric Carcinoma.
1/2018	Dual inhibitor of PI3K and mTOR (NVP-BEZ235) augments the efficacy of fluorouracil on gastric cancer chemotherapy.
1/2018	Sensitization of Gastric Cancer Cells to 5-FU by MicroRNA-204 Through Targeting the TGFBR2-Mediated Epithelial to Mesenchymal Transition.
2/2017	Hepatic artery infusion with raltitrexed or 5-fluorouracil for colorectal cancer liver metastasis.
1/2017	Phase II Study of Hepatic Arterial Infusion Chemotherapy with Oxaliplatin and 5-Fluorouracil for Advanced Perihilar Cholangiocarcinoma.
1/2017	Multicenter Phase 2 Study of Peri-Irradiation Chemotherapy Plus Intensity Modulated Radiation Therapy With Concurrent Weekly Docetaxel for Inoperable or Medically Unresectable Nonmetastatic Gastric Cancer.
1/2016	Inhibition of autophagy by bafilomycin A1 promotes chemosensitivity of gastric cancer cells.

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Hui Chen Research Topics

Disease

465	Neoplasms (Cancer) 07/2024 - 01/2001
133	Inflammation (Inflammations) 04/2024 - 11/2006
115	Infections 03/2024 - 10/2004
80	Fibrosis (Cirrhosis) 04/2024 - 03/2002
78	Neoplasm Metastasis (Metastasis) 05/2024 - 02/2003
64	Hepatocellular Carcinoma (Hepatoma) 03/2024 - 08/2006
45	Reperfusion Injury 02/2024 - 08/2007
45	Carcinogenesis 01/2024 - 01/2010
44	Breast Neoplasms (Breast Cancer) 02/2024 - 10/2006
42	Body Weight (Weight, Body) 07/2024 - 04/2005
41	Colorectal Neoplasms (Colorectal Cancer) 12/2023 - 08/2005
40	Ischemia 10/2023 - 07/2005
39	Stomach Neoplasms (Stomach Cancer) 05/2024 - 10/2011
39	Insulin Resistance 02/2024 - 08/2003
38	COVID-19 07/2024 - 01/2020
36	Wounds and Injuries (Trauma) 04/2024 - 10/2004
36	Hypertension (High Blood Pressure) 01/2024 - 03/2008
35	Lung Neoplasms (Lung Cancer) 02/2024 - 10/2002
34	Obesity 03/2024 - 12/2007
34	Pancreatic Neoplasms (Pancreatic Cancer) 01/2023 - 03/2011
32	Hypoxia (Hypoxemia) 03/2024 - 12/2011
30	Pain (Aches) 05/2024 - 10/2011
30	Myocardial Infarction 10/2023 - 01/2008
28	Hemorrhage 12/2023 - 06/2008
27	Stroke (Strokes) 11/2023 - 08/2005
26	Prostatic Neoplasms (Prostate Cancer) 04/2024 - 03/2008
26	Type 2 Diabetes Mellitus (MODY) 01/2024 - 04/2004
25	Ischemic Stroke 12/2023 - 09/2008
25	Sepsis (Septicemia) 08/2023 - 02/2006
23	Thrombosis (Thrombus) 07/2023 - 08/2010
22	Alzheimer Disease (Alzheimer's Disease) 10/2024 - 03/2008
21	Cataract (Cataracts) 04/2024 - 12/2002
21	Cicatrix (Scar) 03/2024 - 05/2013
21	Diabetes Mellitus 01/2024 - 02/2010
20	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2024 - 02/2008
20	Cardiovascular Diseases (Cardiovascular Disease) 01/2023 - 01/2009
19	Atherosclerosis 03/2024 - 12/2007
19	Shock 03/2024 - 08/2005
19	Liver Cirrhosis (Hepatic Cirrhosis) 11/2023 - 05/2008
19	Hemangioma (Angioma) 01/2022 - 03/2008
19	Lymphatic Metastasis 05/2021 - 08/2005
18	Carcinoma (Carcinomatosis) 10/2023 - 01/2001
18	Acute Coronary Syndrome 01/2023 - 02/2009
17	Glucose Intolerance 11/2023 - 01/2011
17	ST Elevation Myocardial Infarction 01/2023 - 01/2015
16	Mitochondrial Diseases (Mitochondrial Disease) 05/2024 - 04/2015
16	Coronary Artery Disease (Coronary Atherosclerosis) 01/2023 - 02/2009
16	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2023 - 09/2003
15	Disease Progression 10/2024 - 12/2012
15	Tuberculosis (Tuberculoses) 04/2024 - 10/2015
15	Liver Diseases (Liver Disease) 11/2023 - 10/2011

Drug/Important Bio-Agent (IBA)

212	Proteins (Proteins, Gene)FDA Link 04/2024 - 09/2004
123	Biomarkers (Surrogate Marker)IBA 05/2024 - 03/2008
70	CytokinesIBA 04/2024 - 06/2006
66	Messenger RNA (mRNA)IBA 02/2024 - 08/2003
66	Glucose (Dextrose)FDA LinkGeneric 02/2024 - 05/2004
51	MicroRNAs (MicroRNA)IBA 04/2024 - 10/2012
47	LipidsIBA 04/2024 - 06/2003
46	RNA (Ribonucleic Acid)IBA 04/2024 - 01/2008
39	DNA (Deoxyribonucleic Acid)IBA 05/2023 - 06/2005
35	EnzymesIBA 02/2024 - 01/2007
32	VaccinesIBA 12/2023 - 01/2012
30	Insulin (Novolin)FDA Link 11/2023 - 01/2006
30	AntigensIBA 08/2023 - 01/2006
24	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2023 - 09/2003
23	Therapeutic UsesIBA 10/2023 - 01/2012
23	SmokeIBA 01/2023 - 04/2005
22	Long Noncoding RNAIBA 12/2024 - 01/2018
22	AntioxidantsIBA 01/2024 - 08/2009
22	Indicators and Reagents (Reagents)IBA 09/2021 - 08/2005
21	Retinaldehyde (Retinal)IBA 01/2024 - 11/2006
21	Phosphotransferases (Kinase)IBA 01/2024 - 03/2012
21	CollagenIBA 12/2023 - 05/2006
19	LipopolysaccharidesIBA 03/2024 - 01/2011
19	Anti-Bacterial Agents (Antibiotics)IBA 03/2024 - 07/2007
19	Interleukin-6 (Interleukin 6)IBA 10/2023 - 10/2006
18	CateninsIBA 04/2024 - 04/2015
18	AlbuminsIBA 03/2024 - 10/2002
17	Transcription Factors (Transcription Factor)IBA 11/2023 - 01/2012
17	Peptides (Polypeptides)IBA 01/2023 - 04/2005
16	Hormones (Hormone)IBA 01/2024 - 02/2007
16	LigandsIBA 12/2023 - 08/2003
16	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2023 - 02/2008
16	Emodin (Archin)IBA 01/2020 - 12/2010
15	Cisplatin (Platino)FDA LinkGeneric 07/2024 - 10/2002
15	InflammasomesIBA 04/2024 - 02/2016
15	Oxygen (Dioxygen)IBA 02/2024 - 08/2009
15	CholesterolIBA 01/2024 - 01/2016
15	Small Interfering RNA (siRNA)IBA 11/2023 - 09/2010

Therapy/Procedure

249	Therapeutics 05/2024 - 09/2004
82	Drug Therapy (Chemotherapy) 07/2024 - 10/2002
36	Immunotherapy 04/2024 - 02/2010
26	Percutaneous Coronary Intervention 01/2023 - 06/2012
23	Lasers (Laser) 03/2024 - 09/2010
22	Radiotherapy 06/2024 - 09/2004
22	Aftercare (After-Treatment) 03/2024 - 09/2010
17	Ligation 01/2024 - 02/2014
17	Stents 01/2023 - 05/2006
16	Transplantation 04/2024 - 02/2008
15	Injections 01/2024 - 09/2004